透明质酸酯-酰肼, MW 50kDa Hyaluronate-Hydrazide, MW 50kDa
- 发布日期: 2014-05-27
- 更新日期: 2026-01-28
产品详请
1) 货号: HA-352; 2) 中文品名:
透明质酸酯-酰肼, MW 50kDa ; 3) 英文品名: Hyaluronate-Hydrazide, MW 50kDa ; 4) 生产商: PEGWorks; 5) 描述: Hyaluronic Acid is functionalized with hydrazide groups using a short linker adipic acid dihydrazide (ADH). Purity: > 95% powder. Degree of substitution: 5 mol % substitution. Hydrazide is a reactive group specific for aldehydes resulting in acyl hydrazone linkages, and can be used in the linking of glycoproteins or carbohydrates in a site specific fashion following periodate oxidation. Hydrazide coupling may be performed at relatively low pH such as 5.0 to avoid competition reaction by primary amines. HA-Hydrazide with higher or lower hydrazide substitution ratio (e.g. 1% and 10%) may be offered through custom synthesis service. Literature: 1) Functionalized Derivatives of Hyaluronic Acid Oligosaccharides: Drug Carriers and Novel Biomaterials, Bioconjugate Chemistry, 1994,5(4):339–347 2) Hyaluronic acid based scaffolds for tissue engineering—A review, Carbohydrate Polymers 2013, 92(2):1262– 1279;; 6) 规格: 100mg 甄准免费