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透明质酸酯-酰肼, MW 1,500kDa Hyaluronate-Hydrazide, MW 1,500kDa
  • 品牌:PEGWorks
  • 产地:美国
  • 发布日期: 2014-05-27
  • 更新日期: 2026-01-28
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1) 货号: HA-356; 2) 中文品名: 透明质酸酯-酰肼, MW 1,500kDa ; 3) 英文品名: Hyaluronate-Hydrazide, MW 1,500kDa ; 4) 生产商: PEGWorks; 5) 描述: Hyaluronic Acid is functionalized with hydrazide groups using a short linker adipic acid dihydrazide (ADH). Purity: > 95% powder. Degree of substitution: 5 mol % substitution. Hydrazide is a reactive group specific for aldehydes resulting in acyl hydrazone linkages, and can be used in the linking of glycoproteins or carbohydrates in a site specific fashion following periodate oxidation. Hydrazide coupling may be performed at relatively low pH such as 5.0 to avoid competition reaction by primary amines. HA-Hydrazide with higher or lower hydrazide substitution ratio (e.g. 1% and 10%) may be offered through custom synthesis service. Literature: 1) Functionalized Derivatives of Hyaluronic Acid Oligosaccharides: Drug Carriers and Novel Biomaterials, Bioconjugate Chemistry, 1994,5(4):339–347 2) Hyaluronic acid based scaffolds for tissue engineering—A review, Carbohydrate Polymers 2013, 92(2):1262– 1279;; 6) 规格: 100mg 甄准免费
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